An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training
Reprogramming…#epigenome & transcriptome in…muscle after training http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4622000/ Delta(Me) from #exercise in 1 leg v. other
QT:{{”
Exercise has long been known to have an effect on health, lowering the incidence of cardiovascular disease, obesity, and type 2 diabetes. Recently, it has been found that exercise can have a direct effect on DNA methylation and gene expression. A group of 23 subjects exercised one leg but not the other for 45 minutes four times a week for three months. At the end of this period, the methylation and gene expression patterns were different in the exercised leg relative to the one that did not exercise, indicating a direct effect of exercise on
epigenetics.
“}}
Quote from:
https://books.google.com/books?id=qotyCwAAQBAJ&pg=PA91&lpg=PA91&dq=Exercise+has+long+been+known+to+have+an+effect+on+health,+lowering+the+incidence+of+cardiovascular+disease,+obesity,+and+type+2+diabetes.+Recently,+it+has+been+found+that+exercise+can+have+a+direct+effect+on+DNA+methylation+and+gene+expression.+A+group+of+23+subjects+exercised+one+leg+but+not+the+other+for+45+minutes+four+times+a+week+for+three+months.+At+the+end+of+this+period,+the+methylation+and+gene+expression+patterns+were+different+in+the+exercised+leg+relative+to+the+one+that+did+not+exercise,+indicating+a+direct+effect+of+exercise+on+epigenetics.&source=bl&ots=paSuwD6wvw&sig=gwFDNYvSMRlkFouTcaoyf9q3c20&hl=en&sa=X&ved=0ahUKEwjZzv7imu3KAhXK5SYKHaP6DdEQ6AEIHjAA#v=onepage&q=Exercise%20has%20long%20been%20known%20to%20have%20an%20effect%20on%20health%2C%20lowering%20the%20incidence%20of%20cardiovascular%20disease%2C%20obesity%2C%20and%20type%202%20diabetes.%20Recently%2C%20it%20has%20been%20found%20that%20exercise%20can%20have%20a%20direct%20effect%20on%20DNA%20methylation%20and%20gene%20expression.%20A%20group%20of%2023%20subjects%20exercised%20one%20leg%20but%20not%20the%20other%20for%2045%20minutes%20four%20times%20a%20week%20for%20three%20months.%20At%20the%20end%20of%20this%20period%2C%20the%20methylation%20and%20gene%20expression%20patterns%20were%20different%20in%20the%20exercised%20leg%20relative%20to%20the%20one%20that%20did%20not%20exercise%2C%20indicating%20a%20direct%20effect%20of%20exercise%20on%20epigenetics.&f=false
Tags: epigenome, exercise, gpm0mg, motrpac, quote, u24motr
This entry was posted
on Friday, February 12th, 2016 at 11:54 pm and is filed under SciLit, Uncategorized.
You can follow any responses to this entry through the RSS 2.0 feed.
Responses are currently closed, but you can trackback from your own site.