linkstream2 microblog

http://www.designntrend.com/articles/32141/20141223/ai-teams-up-genomics-find-disease-causing-mutations.htm

Doesn’t seem to work in the current IOS

http://www.iphoneincanada.ca/how-to/how-to-show-labeled-email-with-google-sync-on-iphone/

QT:{{”
Goldberg began working at PARC in 1973 as a laboratory and research assistant, and eventually became manager of the System Concepts Laboratory where she, Alan Kay, and others developed Smalltalk-80, which both developed the object-oriented approach of Simula 67 and introduced a programming environment of overlapping windows on graphic display screens. Not only was Smalltalk’s innovative format simpler to use, it was also customizable and objects could be transferred among applications with minimal effort.[1][2] Goldberg and Kay also were involved in the development of design templates, forerunners of the design patterns commonly used in software design.[3] In 1988 Goldberg left PARC to co-found ParcPlace Systems, a company that created development tools for Smalltalk-based applications.
“}}

https://en.wikipedia.org/wiki/Adele_Goldberg_(computer_scientist)

Supposedly incensed at the “kimono opening”, viz

QT:{{”

Apple was already one of the hottest tech firms in the country. Everyone in the Valley wanted a piece of it. So Jobs proposed a deal: he would allow Xerox to buy a hundred thousand shares of his company for a million dollars—its highly anticipated I.P.O. was just a year away—if PARC would “open its kimono.” A lot of haggling ensued. Jobs was the fox, after all, and PARC was the henhouse. What would he be allowed to see? What wouldn’t he be allowed to see? Some at PARC thought that the whole idea was lunacy, but, in the end, Xerox went ahead with it. One PARC scientist recalls Jobs as “rambunctious”—a fresh-cheeked, caffeinated version of today’s austere digital emperor. He was given a couple of tours, and he ended up standing in front of a Xerox Alto, PARC’s prized personal computer.
“}}

http://www.newyorker.com/magazine/2011/05/16/creation-myth

http://en.wikipedia.org/wiki/Bill_Atkinson

http://archive.org/stream/byte-magazine-1984-02/1984_02_BYTE_09-02_Benchmarks#page/n59/mode/2up

Newly created photocard, viz:
http://www.billatkinson.com/Pages/aboutPhotoCard.html

Is it related to the original HyperCard?

QT:{{”

While the documentation shipped with the original Lisa only ever referred to it as The Lisa, officially, Apple stated the name was an acronym for Local IntegratedSystem Architecture or “LISA”.[6] Since Steve Jobs’ first daughter (born in 1978) was named Lisa Nicole Brennan, it was normally inferred that the name also had a personal association, and perhaps that the acronym was invented later to fit the name. Andy Hertzfeld[7] states the acronym was reverse engineered from the name “Lisa” in autumn 1982 by the Apple marketing team, after they had hired a marketing consultancy firm to come up with names to replace “Lisa” and “Macintosh” (at the time considered by Jef Raskin to be merely internal project codenames) and then rejected all of the suggestions. Privately, Hertzfeld and the other software developers used “Lisa: Invented Stupid Acronym”, a recursive backronym, while computer industry pundits coined the term “Let’s Invent Some Acronym” to fit the Lisa’s name. Decades later, Jobs would tell his biographer Walter Isaacson: “Obviously it was named for my daughter.”[8] “}}

http://en.wikipedia.org/wiki/Apple_Lisa

Correlated Genome Associations to Quantitative Trait #Network (QTN) http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1000587
Uses fused #lasso for estimation of relationships

Kim & Xing (’09) provide a new method for calculating how genetic
markers associate with phenotypes by incorporating phenotype
connectivity features into the correlation structure between markers
and phenotypes. Their model attempts to quantify pleiotropic
relationships between different phenotypes and assumes a common
genotypic origin for the existence of clusters of correlated
phenotypes, which their algorithm uses to reduce the number of
significant genetic markers. In particular, Kim and Xing present a
method for performing quantitative trait analysis that implements two
novel approaches to inferring the contribution of a
[marker/allele/SNP/gene/locus] to a quantitative trait. The first is
organization of traits into a quantitative trait network (QTN). The
second is the utilization of fused lasso, a variation of multivariate
regression that seeks to minimize the number of non-zero coefficients
and least squared error. These two approaches are combined in an
attempt to minimize noise (in the form of small coefficients for SNP’s
that don’t really make a contribution) and focus on truly relevant
SNP’s while dealing with the correlated nature of quantitative
traits. Based on two datasets – simulated HapMap data and
data from the Severe Asthma Research Program – the authors show marked
improvement in accuracy and reduction of false positives over simpler
multivariate regression methods.

http://www.macworld.co.uk/how-to/ipad/how-download-youtube-videos-your-ipad-so-you-can-watch-them-offline-3441965/
Vdownloader – but doesn’t currently work with youtube!

Roche Sequencing acquires Bina Technologies
https://www.genomeweb.com/business-news/roche-acquires-bina-technologies Wow: 454, Nimblegen & now Bina! (NB: I’ve consulted for Bina & 454.)

Recommends Manual for $2

http://www.nytimes.com/2014/10/02/technology/personaltech/smartphone-photography-evolves-with-camera-apps-and-related-tools.html

Worked with Nolan Bushnell on Atari & was an early employer of Steve Jobs

http://en.wikipedia.org/wiki/Allan_Alcorn