linkstream2 microblog

http://techcrunch.com/2014/11/10/microsoft-office-apps-skyrocket-to-the-top-of-the-app-store-following-pricing-changes/?ncid=rss&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+Techcrunch+%28TechCrunch%29

http://www.nature.com/news/microbiome-science-threatened-by-contamination-1.16327

http://news.sciencemag.org/biology/2014/11/biorxiv-1-year-promising-start

Crowd-sourcing w AMZN mechanical turk

http://www.crowdflower.com/

also odesk
http://www.behind-the-enemy-lines.com/2012/02/mturk-vs-odesk-my-experiences.html

i0biods14 => #biodata14
i0pcawg14 => i0pcawg14+exrna

https://storify.com/markgerstein/favorite-tweets-from-biological-data-science-i0bio

http://linkstream2.gerstein.info/tag/i0pcawg14
http://linkstream2.gerstein.info/tag/i0biods14

http://lectures.gersteinlab.org/summary/nc-annotation-sect-from–PAWG-2-5-9-14_prep_for_Boston_mtg

http://lectures.gersteinlab.org/summary/Framework-to-prioritize-Regulatory-variants-Progressive-summarization-of-large-scale-data–20141108-i0biods14/

– how to expand beyond 12 tumors?
– reclassification of lung squam. lung adeno. & subdivisions of breast cancer

Hoadley et al. … Stuart

http://www.sciencedirect.com/science/article/pii/S0092867414008769?via=ihub

“mutsig2CV”

http://www.ncbi.nlm.nih.gov/pubmed/24390350

MutSig – 1.0 – Getz et al. Science 2007
MutSigCV – CV – covariates
mutations need to cluster at hotspots & in functional regions

http://www.sciencemag.org/content/317/5844/1500.2

Science 14 September 2007:
Vol. 317 no. 5844 p. 1500
DOI: 10.1126/science.1138764

TECHNICAL COMMENTS

Comment on “The Consensus Coding Sequences of Human Breast and Colorectal Cancers”

Gad Getz1,*,†,
Holger Höfling2,*,
Jill P. Mesirov1,
Todd R. Golub1,3,4,5,6,
Matthew Meyerson1,3,
Robert Tibshirani2,7,
Eric S. Lander1,6,8

Nice heatmap tool
http://www.gitools.org/home

contains a mechanisms pipeline, similar to breakseq

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3704973/#!po=42.5926

Cell. Author manuscript; available in PMC May 9, 2014.
Cell. May 9, 2013; 153(4): 919–929.
doi: 10.1016/j.cell.2013.04.010
PMCID: PMC3704973
NIHMSID: NIHMS475485

Diverse mechanisms of somatic structural variations in human cancer genomes Lixing Yang,1 Lovelace J. Luquette,1 Nils Gehlenborg,1,2 Ruibin Xi,1 Psalm S. Haseley,1,3 Chih-Heng Hsieh,4Chengsheng Zhang,4 Xiaojia Ren,3 Alexei Protopopov,5 Lynda Chin,5 Raju Kucherlapati,3,6 Charles Lee,4 and Peter J. Park1,3,7,*