linkstream2 microblog

http://bostinno.streetwise.co/2014/07/22/teradata-hadapt-deal-hadapt-acquired-by-teradata-to-build-center-of-excellence-in-cambridge/

This is a key paper for both for big data, and for oncology. Although the N isn’t massive (4,000), it illustrates a completely different way of thinking about the classification of neoplasia. Additionally, they demonstrate that this new classification adds to current models predicting survival.

http://uncnews.unc.edu/2014/08/07/classifying-cancer/
Largest cancer genetic analysis reveals new way of classifying cancer

(Chapel Hill, N.C. – August 7, 2014) – Researchers with The Cancer Genome Atlas (TCGA) Research Network have completed the largest, most diverse tumor genetic analysis ever conducted, revealing a new approach to classifying cancers. The work, led by researchers at the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill and other TCGA sites, not only revamps traditional ideas of how cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug
development…..

calendar exporter:

http://www.gcal2excel.com/

It is simple but does the work you need: calendar exporting, event filter based on keywords and simple statistics.

http://www.americanscientist.org/issues/feature/2014/5/master-of-missing-elements/1

http://yaledailynews.com/blog/2014/02/06/yales-top-earners-defended/

Is the #glycemicindex a useful measure of #carbohydrate
metabolism?http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=49410 An issue: Individual variation in sugar response

Functional characterization of… developmental #enhancers in vivo: 3.5k of 7.7k tested active in fly embryo stages
http://www.nature.com/nature/journal/v512/n7512/abs/nature13395.html

http://www.sciencemag.org/content/334/6062/1518.short

http://www.nytimes.com/2014/08/12/movies/robin-williams-oscar-winning-comedian-dies-at-63.html?smid=tw-nytimes&_r=0

Transduction of nonrepetitive DNA mediated by L1 retrotransposition in #cancer #genomes
http://www.sciencemag.org/content/345/6196/1251343.abs associated w/ hypomethylation

Jose M. C. Tubio1,
Yilong Li1,*,
Young Seok Ju1,*,
Inigo Martincorena1,
Susanna L. Cooke1,
…
Adrienne M. Flanagan30,31,
P. Andrew Futreal1,32,
Sam M. Janes3,
G. Steven Bova12,
Michael R. Stratton1,
Ultan McDermott1,
Peter J. Campbell1,10,33,‡

QT:{{”
Retrotransposons are DNA repeat sequences that are constantly on the move. By poaching certain cellular enzymes, they copy and insert themselves at new sites in the genome. Sometimes they carry along adjacent DNA sequences, a process called 3′ transduction. Tubio et al. found that 3′ transduction is a common event in human tumors. Because this process can scatter genes and regulatory sequences across the genome, it may represent yet another mechanism by which tumor cells acquire new mutations that help them survive and grow.
“}}