linkstream2 microblog

http://www.examiner.com/review/a-to-z-oregon-pino-gris-2012

QT:”
We estimate that approximately 73% of all protein-coding SNVs and approximately 86% of SNVs predicted to be deleterious arose in the past 5,000–10,000 years.
”

6,515 #exomes reveals the recent origin of most human protein-coding variants: ~75% #SNVs arose in last ~7.5K yrs
http://www.nature.com/nature/journal/v493/n7431/full/nature11690.html

The bread #wheat genome using… shotgun sequencing: ~5X human, from 3 diff. component genomes, many #pseudogenes
http://www.nature.com/nature/journal/v491/n7426/full/nature11650.html

http://www.slate.com/blogs/future_tense/2013/08/30/glenn_greenwald_nsa_leaks_u_k_tries_to_crack_passwords_on_guardian_journalist.html

http://www.theatlantic.com/magazine/archive/2013/09/the-way-we-lie-now/309431/

JASON’s report on personal genomics

http://www.fas.org/irp/agency/dod/jason/hundred.pdf

http://www.sciencemag.org/content/341/6149/947.full?rss=1
[News & Analysis] Cell Biology: NIH Effort Gambles on Mysterious Extracellular RNAs
A $17 million research program, announced this month by the U.S. National Institutes of Health, aims to determine whether RNA molecules are deliberately released by cells as hormonelike signals—and whether such extracellular RNAs can be harnessed for diagnosis and treatment of human diseases.
Author: Mitch Leslie

http://www.informationweek.com/education/online-learning/moocs-lead-duke-to-reinvent-on-campus-co/240160438?cid=NL_IWK_Edu_240160438&elq=b0d3defe37b74646b0877e4315a52988

http://well.blogs.nytimes.com/2013/08/29/ask-well-is-it-better-to-bike-or-run/?ref=health&smid=tw-nytimes&_r=0

by C Zimmer
http://www.wired.com/wiredscience/2013/08/the-fall-and-rise-of-gene-therapy/all/
Fall & Rise of #GeneTherapy: from J Gelsinger’s death to the development of new viral vectors
http://www.wired.com/wiredscience/2013/08/the-fall-and-rise-of-gene-therapy/all/