linkstream2 microblog

http://www.biotechniques.com/BiotechniquesJournal/2012/July/The-new-molecular-gastronomy-or-a-gustatory-tour-of-network-analysis/biotechniques-332722.html

http://www.biostars.org/post/show/4751/titv-ratio-confirms-snp-discovery-is-this-a-general-rule/ QT:”
The transition transversion ratio in human is observed to be around 2.1 and this can be used as a confirmation for the filtering in a snp discovery project.
”
http://genome.sph.umich.edu/wiki/SNP_Call_Set_Properties
QT:”
Proportion of dbSNPs
Most of the genetic variants in any one individual have been previously observed in other individuals. Thus, it is usually a good diagnostic to investigate what fraction of variants in an individual genome have been previously described in dbSNP.
….The dbSNP database is being constantly updated so that currently (mid-2010) we’d expect >90% of the variants in an individual genome to have been previously discovered….
Transition to Transversion Ratio
…transitions (changes from A <-> G and C <-> T) are expected to occur twice as frequently as transversions (changes from A <-> C, A <-> T, G <-> C or G <-> T). Thus, another useful diagnostic is the ratio of transitions to transversions in a particular set of SNP calls. ….
Across the entire genome the ratio of transitions to transversions is typically around 2. In protein coding regions, this ratio is typically higher, often a little above 3. The higher ratio occurs because, especially when they occur in the third base of a codon, transitions are much more likely to change the encoded amino acid. “

It looks really well done.

https://github.com/hakimel/reveal.js

There is a demo here:

http://lab.hakim.se/reveal-js/

Seem to have cancer SNV calls all over the genome.
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11273.html

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2359.html

http://m.gizmodo.com/5931587/sony-rx100-review-this-camera-singlehandedly-makes-point+and+shoots-relevant-again

http://www.nucleartownhall.com/blog/william-tucker-if-you-want-to-understand-nuclear-learn-algebra/

http://www.nature.com/news/why-great-olympic-feats-raise-suspicions-1.11109

http://online.wsj.com/article/SB10000872396390443343704577549742029854090.html

http://online.wsj.com/article/SB10000872396390443343704577549311353156318.html