Posts Tagged ‘pseudogenes’
Cell – Expressed Pseudogenes in the Transcriptional Landscape of Human Cancers
Saturday, July 14th, 2012http://www.cell.com/retrieve/pii/S009286741200640X?cc=y
Transcribed pgenes perhaps acting as ceRNAs very tissue specific, in a variety of cancers
Most less conservative threshold on calling transcription than in encodeprodpgenes
Landscape of Somatic Retrotransposition in Human Cancers – Science
Thursday, July 5th, 2012http://www.sciencemag.org/content/early/2012/06/27/science.1222077.abstract
Park lab led analysis of TCGA data
Proto-genes and de novo gene birth : Nature : Nature Publishing Group
Saturday, June 30th, 2012primate OR pseudogene links
Friday, June 22nd, 2012links to the correction/retraction of the Gilad et al. paper on primate olfactory receptors:
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.0050148
Matsui et al. paper looking at genome-wide ORs:
http://mbe.oxfordjournals.org/content/27/5/1192.short
A general lack of compensation for gene dosage in yeast
Sunday, June 10th, 2012http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890323/?tool=pubmed
Interesting in relation to duplication, numbers of pseudogenes and gene expression levels.
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
Sunday, June 10th, 2012http://www.pnas.org/content/106/18/7507.long
effects of polymorphisms in uORFs in the human population… perhaps worth a larger survey
pseudogenes that might have saved us !
Wednesday, June 6th, 2012http://www.sciencedaily.com/releases/2012/06/120604155554.htm?fb_ref=.T829TjfxGmI.like&fb_source=home_oneline Specific inactivation of two immunomodulatory SIGLEC genes during human evolution
http://www.pnas.org/content/early/2012/05/30/1119459109.abstract