linkstream2 microblog

http://www.ensembl.info/blog/2012/08/06/variation-consequences/
UCSC, ICGC and dbSNP will follow…

Seem to have cancer SNV calls all over the genome.
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11273.html

Courtesy of NB & JC :

QT:

“Exploiting the fact that a hydrogen ion is released whenever a nucleotide attaches to a strand of DNA, sensors in Ion Torrent’s microchip have been designed to detect this chemical signature. “

“ they’ve (Oxford Nanopores) embedded a protein pore into a synthetic polymer membrane. The strand of DNA being sequenced is then passed through the pore and as each nucleotide goes through, it registers as a different electrical signal detected by Oxford’s machine.”

“Complete Genomics expects to churn out the complete sequences of 100,000 to 1 million genomes in the near future as they ramp up operations!”

http://singularityhub.com/2012/07/20/battle-of-the-next-generation-dna-sequencers-heating-up/

http://www.nytimes.com/2012/07/12/health/research/rare-gene-mutation-is-found-to-stave-off-alzheimers.html?pagewanted=all

http://www.sciencemag.org/content/early/2012/06/27/science.1222077.abstract
Park lab led analysis of TCGA data

http://www.nature.com/news/correction-algorithms-extend-the-reach-of-genome-sequencing-1.10924

NYT
http://www.nytimes.com/2012/05/08/science/another-genetic-quirk-of-the-solomon-islands-blond-hair.html?

Science paper
http://www.sciencemag.org/content/336/6081/554

From SB: It is always cool to associate a variant to a clear phenotype ( even it it isn’t the causal variant).

http://www.genomeweb.com//node/1062556?hq_e=el&hq_m=1261329&hq_l=1&hq_v=82c4d3e4a4

http://www.nature.com/news/a-trip-to-the-gym-alters-dna-1.10176

http://www.economist.com/node/21534747