linkstream2 microblog

http://www.nytimes.com/2012/05/31/science/the-tomato-ripe-juicy-and-bursting-with-genes.html

bioinformatics + expt. reveal particular seq. motif (YCAY) important in splicing in brains
http://www.nature.com/nature/journal/v444/n7119/abs/nature05304.html

Nice overview of Clipseq/HITS-CLIP
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222227/
QT:”
This advantage relates to the mechanism of UV-mediated crosslinking, which, although incompletely understood, is believed to involve absorption of UV light by nucleic acid bases44 to induce ground state electrons to a singlet higher-energy state that enables the electron to partake in a chemical reaction in which a new covalent bond is formed…
“

BBC article:
http://www.bbc.co.uk/news/science-environment-20617312

http://www.cell.com/AJHG/fulltext/S0002-9297%2812%2900538-1
Deleterious- and Disease-Allele Prevalence in Healthy Individuals: Insights from Current Predictions, Mutation Databases, and
Population-Scale Resequencing
Yali Xue1, Yuan Chen1, Qasim Ayub1, Ni Huang1, Edward V. Ball2, Matthew Mort2, Andrew D. Phillips2, Katy Shaw2, Peter D. Stenson2, David N. Cooper2, Chris Tyler-Smith1, , and the 1000 Genomes Project Consortium

http://genome.cshlp.org/content/early/2012/11/01/gr.141382.112
analysis of 95 tumor genomes

QT:”
Bread wheat (Triticum aestivum) is a globally important crop, accounting for 20 per cent of the calories consumed by humans….Here we report the sequencing of its large, 17-gigabase-pair, hexaploid genome using 454 pyrosequencing, and comparison of this with the sequences of diploid ancestral and progenitor genomes. We identified between 94,000 and 96,000 genes.
”
http://www.nature.com/nature/journal/v491/n7426/full/nature11650.html?WT.ec_id=NATURE-20121129

http://www.bio-itworld.com/2012/11/28/physician-scientist-robert-darnell-named-scientific-director-new-york-genome-center.html

http://www.nature.com/scientificamerican/journal/v299/n1/full/scientificamerican0708-56.html Gary Stix

http://www.wired.com/wiredscience/2012/12/science-figures-2012

http://genome.cshlp.org/content/22/12/2529.full