Archive for the ‘SciLit’ Category

Crinkly Curves » American Scientist

Monday, April 29th, 2013

http://www.americanscientist.org/issues/id.16035,y.0,no.,content.true,page.1,css.print/issue.aspx

An Introduction to Social Media for Scientist – might be a fun read

Sunday, April 28th, 2013

An Introduction to Social Media for Scientists
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001535 “Online social media tools can be some of the most rewarding and informative resources for scientists—IF you know how to use them.”

Relating CNVs to transcriptome data at fine resolution: Assessment of the effect of variant size, type, and overlap with functional regions

Friday, April 19th, 2013

http://genome.cshlp.org/content/21/12/2004.long
initial cnv eqtls

From pseudogenes to proteins

Friday, April 19th, 2013

Gencode perspective on massspec of pseudogenes
http://www.nature.com/nmeth/journal/v8/n6/full/nmeth0611-448b.html

PLOS Medicine: Why Most Published Research Findings Are False

Monday, April 15th, 2013

http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0020124

metacyc/kegg comparison paper

Friday, April 12th, 2013

a detailed comparison of
MetaCyc versus KEGG:
MetaCyc contains more than 10 times as many metabolic pathways as KEGG “modules” (the comparable type of pathway in KEGG).
http://www.biomedcentral.com/1471-2105/14/112/abstract

Somatic evolutionary genomics: Mutations during development cause highly variable genetic mosaicism with risk of cancer and neurodegeneration

Tuesday, April 9th, 2013

Paper giving a conceptual framework to somatic mosaicism

http://www.pnas.org/content/107/suppl.1/1725.full

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

Tuesday, April 9th, 2013

Many denovo mutations in autism but few recurrant ones.

“Here they examined over 2000 probands and found only a handful of recurrent mutations…. Also In this article they mention a beta catenin-chromatin remodelling network that seems to encompass a majority of these genes”

http://www.sciencemag.org/content/338/6114/1619

Universal distribution of component frequencies in biological and technological systems

Monday, April 8th, 2013

http://www.pnas.org/content/early/2013/03/21/1217795110.abstract http://gizmodo.com/5993071/dna-is-the-linux-of-the-natural-world

the biggest challenges in bioinformatics

Monday, April 8th, 2013

http://www.nature.com/embor/journal/v14/n4/pdf/embor201334a.pdf