Archive for August, 2014
GraphiTabs Groups, Searches and Suspends Tabs in a Tree-Style View
Monday, August 25th, 2014Kickstarter for documentary on network science
Monday, August 25th, 2014Laplace’s law of succession | Understanding Uncertainty
Monday, August 25th, 2014IEEE Xplore Abstract – A Comparative Analysis of Ensemble Classifiers: Case Studies in Genomics
Sunday, August 24th, 2014Pandey mentions: Comparative Analysis of #Ensemble Classifiers [eg mean agg. or stacking]…in Genomics
http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=6729565&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D6729565 #kdd2014
performance-diversity tradeoff: should one incl. higher performance, lower diversity ones…. but still adding diversity is good
related to https://github.com/shwhalen/datasink
The Garmin Fenix 2 Brings The Running Watch Into A Dystopian Future | TechCrunch
Sunday, August 24th, 2014A Better Credit Card – NYTimes.com
Saturday, August 23rd, 2014Where the Five-Day Workweek Came From – The Atlantic
Saturday, August 23rd, 2014PLOS Biology: Where Do Introns Come From?
Saturday, August 23rd, 2014Where Do #Introns Come From? A suggestion: exons with premature stops; has implications for #pseudogene formation http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.0060283
QT:{{
We have proposed a novel hypothesis for the origin of spliceosomal
introns, invoking endogenous production within translatable sequences
(at least in the case of protein-coding genes), facilitated by the
activity of cellular surveillance mechanisms. Despite the mutational
hazard associated with intron presence and proliferation [136], we
argue that, at least initially, introns might represent a favorable
life line for an allele that has acquired an ORF-disrupting mutation.
In this sense, in-frame stop codons need not be dead ends, as often
believed, but rather sequences that occasionally facilitate the
evolution of eukaryotic gene structure, possibly favoring not only
intronization, but also processes such as exonization (following a PTC
loss [137]). Further experimental validation of our hypothesis would
not only support the idea that intron birth/death rates depend on both
the population-genetic [136] and the intracellular environment, but
also shed light on a surprising aspect of the evolution of eukaryotic
gene structure, i.e., the ongoing, stochastic process of mutual
conversion between exons and introns within genes.
"}}
Rise of the Five-Figure Bicycle – WSJ
Saturday, August 23rd, 2014Rise of the 5-Figure #Bicycle http://online.wsj.com/articles/rise-of-the-five-figure-bicycle-1408489679 C-fiber, disc brakes & electronic shifting gives rise to 7 Treks >$11K