Archive for March, 2013
RNA studies under fire : Nature News & Comment
Thursday, March 7th, 2013Ready for More 10,000 Cancer Genomes Projects? – ScienceInsider
Thursday, March 7th, 2013The future of the bookstore: A real cliffhanger | The Economist
Wednesday, March 6th, 2013Study Points to Declining Life Span for Some U.S. Women – WSJ.com
Tuesday, March 5th, 201376 v 81 but gap narrowing
http://online.wsj.com/article/SB10001424127887323494504578340732591601900.html?mod=wsj_share_tweet
The epidemic of allergy and asthma : Nature
Monday, March 4th, 2013~15 year old review but still interesting
http://www.nature.com/nature/journal/v402/n6760supp/full/402b002a0.html
Cancer Cell – Epigenetic Abnormalities in Cancer Find a “Home on the Range”
Monday, March 4th, 2013https://www.cell.com/cancer-cell/abstract/S1535-6108(12)00520-X?switch=standard
ScienceDirect.com – Chemistry & Biology – As Personal Genomes Join Big Data Will Privacy and Access Shrink?
Monday, March 4th, 2013http://www.sciencedirect.com/science/article/pii/S1074552113000094
Volume 20, Issue 1, 24 January 2013, Pages 1–2
As Personal Genomes Join Big Data Will Privacy and Access Shrink? Jeanne Erdmann
Chemistry & Biology
QT:{
We live immersed in a world of big data. Every Internet click is tracked and noted—where we browse, what we view, how long we browse, where we shop, what we buy, what we “like.” In fact, many of our daily activities are monitored. Surveillance cameras track vehicles as they pass through intersections and track pedestrians as they walk down sidewalks; cameras note our transactions at ATMs. While it’s understandable to worry that so much surveillance invades our privacy, we may be overlooking the most personal information of all: the order of base pairs in our genomes. Each day, DNA sequencers worldwide churn out personal genomic data, which are then folded into large databases, some of which are open access, others of which are privately held. All of these big data collections carry value, and they’re mined for that value, whether it’s to tell Amazon what kind of books we like or to tell researchers whether our DNA carries variations that link to an increased risk for disease.
“I do think that those are parallel discussions,” says Mark Gerstein, PhD, a professor of bioinformatics at Yale University in New Haven. “But if you talk to most genomicists they don’t usually connect genomics with large-scale data mining on the web or in life.” They’re the same, Gerstein says. People may be attuned to the concept of secrets and privacy of personal information but not when it comes to mining terabytes of personal genomic information. The distinction is critical, because our tastes in books and music may evolve over the years, but our genomes never change.
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examples from paper to application in Kbase
Monday, March 4th, 2013Here are two examples to transfer research paper to application in Kbase
http://www.kbase.us/for-users/tutorials/prom-service/
http://www.pnas.org/content/107/41/17845.abstract
http://www.kbase.us/developer-zone/api-documentation/phispy-service/ http://www.ncbi.nlm.nih.gov/pubmed/22584627