Posts Tagged ‘funding’

NOT-OD-16-011: Implementing Rigor and Transparency in NIH & AHRQ Research Grant Applications

Sunday, February 14th, 2016

New grant format w/ prelim. results under significance v. approach as now @NIH notice is cryptic. People’s thoughts?

need to use strength & weakness for each citation.

see also:

One of the changes to this Chapter pertains to the format for the Approach subsection, which is reproduced, above. “Justification and Feasibility” and its two subdivisions have been lined out because, with the new approach that we recommend, they are no longer part of the Approach subsection. (We have moved them to the Significance subsection, Chapter 9). Without those components, the formatting for each aim “collapses” to include the Introductory Paragraph, Research Design, Expected Outcomes and Potential Problems & Alternative Strategies.


Updates to Research Strategy Guidance
By November 25, 2015 application guide instructions will be updated to include the following additional guidance for the Significance and Approach sections of the Research Strategy, in addition to the existing instructions.
Describe the scientific premise for the proposed project, including consideration of the strengths and weaknesses of published research or preliminary data crucial to the support of your application. Approach
Describe the experimental design and methods proposed and how they will achieve robust and unbiased results.

SF424 (R&R) Application and Electronic Submission Information for NIH

Tuesday, November 10th, 2015


11. Descriptive Title of Applicant’s Project

Enter a brief descriptive title of the project. This field is required.

A “new” application must have a different title from any other PHS project with the same PD/PI. A “resubmission” or “renewal” application should normally have the same title as the previous grant or application. If the specific aims of the project have significantly changed, choose a new title.

A “revision” application must have the same title as the currently funded grant.

NIH and other PHS agencies limit title character length to 81 characters, including the spaces between words and punctuation. Titles in excess of 81 characters will be truncated. Be sure to only use standard characters in the descriptive title: A through Z, a through z, 0 through 9, space ( ), and underscore (_).



Prepare the application using Arial, Helvetica, Palatino Linotype, or Georgia typeface in black font color. After text attachments are converted to PDF, font size in each final PDF document must be at least 11 points (or larger). (A Symbol font may be used to insert Greek letters or special characters; the font size requirement still applies.) Since some PDF converters may reduce font sizes, it is important to confirm that type density in each final PDF document, including both characters and spaces, is no more than 15
characters+spaces per linear inch and no more than six lines per vertical inch.

Note: 72 points/inch so 6 lines/inch at 11pt type translates into a line spacing of 11 pts + 1pt per line.

Paper Size and Page Margins

Final PDF documents should be formatted to be no larger than standard paper size (8 ½” x 11). The final PDF document should have at least one-half inch margins (top, bottom, left, and right) for all pages. No information should appear in the margins, including the PI’s name and page numbers.

Figures, Graphs, Diagrams, Charts, Tables, Figure Legends, and Footnotes You may use a smaller type size but it must be in a black font color, readily legible, and follow the font typeface requirement. Color can be used in figures; however, all text must be in a black font color, clear and legible.

Dartmouth Outlines Fix for Geisel Deficit | Valley News

Monday, November 2nd, 2015

Here is a news about Dartmouth Medical School.

The most recent informations is that departments will be kept, but some departments will be removed or merged.

Does the Application Title Have a Maximum Length? | NIH Extramural Nexus

Saturday, September 12th, 2015

Limitation to 81 characters

A New Initiative on Precision Medicine — NEJM

Tuesday, September 8th, 2015

A New Initiative on Precision Medicine Notable: focus on #cancergenomics & mention of endophenotypes & #QS data

Francis S. Collins, M.D., Ph.D., and Harold Varmus, M.D.
N Engl J Med 2015; 372:793-795February 26, 2015DOI: 10.1056/NEJMp1500523

“These features make efforts to improve the ways we anticipate, prevent, diagnose, and treat cancers both urgent and promising. Realizing that promise, however, will require the many different efforts reflected in the President’s initiative. To achieve a deeper understanding of cancers and discover additional tools for molecular diagnosis, we will need to analyze many more cancer genomes. ….
The cancer-focused component of this initiative will be designed to address some of the obstacles that have already been encountered in “precision oncology”: unexplained drug resistance, genomic
heterogeneity of tumors, insufficient means for monitoring responses and tumor recurrence, and limited knowledge about the use of drug combinations.

The initiative’s second component entails pursuing research advances that will enable better assessment of disease risk, understanding of disease mechanisms, and prediction of optimal therapy for many more diseases, with the goal of expanding the benefits of precision medicine into myriad aspects of health and health care.

The initiative will encourage and support the next generation of scientists to develop creative new approaches for detecting, measuring, and analyzing a wide range of biomedical information — including molecular, genomic, cellular, clinical, behavioral, physiological, and environmental parameters. Many possibilities for future applications spring to mind: today’s blood counts might be replaced by a census of hundreds of distinct types of immune cells; data from mobile devices might provide real-time monitoring of glucose, blood pressure, and cardiac rhythm; genotyping might reveal particular genetic variants that confer protection against specific diseases…

Useful NIH Funding Data on Bioinformatics Education

Sunday, September 6th, 2015

BD2K funded programs so far…

NIGMS Comp Bio & Bioinfo funded predoctoral programs

THE NLM funded Biomedical Informatics training programs

The Disappearing Young Scientists

Friday, April 3rd, 2015

Disappearing Young Scientists Michael Levitt on implications of #budget cuts for starting researchers HT @oselsayed

What’s behind the shortage? Mr. Daniels suggests several reasons, including longer postdoctoral training; a system of applications, demonstrable data and peer review, and a shift in research costs to universities—which typically narrows awards to seasoned, tenured researchers. But perhaps the simplest explanation came from Nobel laureate Michael Levitt of Stanford, who said last year that senior scientists were once able to renew their existing grants and let young scientists compete for unawarded grant money. Now after budget cuts, older scientists are competing “against the kids,” and usually winning.

In Silver Case, U.S. Cites Link to Litigation Tied to Asbestos

Friday, January 30th, 2015


n 2005, just as Mr. Silver’s referral income from the Weitz firm began to balloon, records show that he directed a state grant worth $250,000 to Dr. Taub for asbestos research, ostensibly related to the Sept. 11, 2001, terrorist attacks. In October 2006, Dr. Taub wrote to Mr. Silver to request another $250,000 grant. A few months later, the money arrived.

Both times, the plans submitted by Dr. Taub’s center said the money would go toward studying the general treatment of mesothelioma, making only passing reference to those who may have been exposed to asbestos after the attacks on the World Trade Center.

For his part, Dr. Taub served as an expert witness for the Weitz firm as recently as a 2013 case in federal court in Pennsylvania. Legal records show that his rate for working on the case was $1,750 per hour, plus $7,500 per day for testimony when overnight travel was required.

New NIH Biosketch–Helpful Website

Friday, January 23rd, 2015

Here is a link for some helpful information on the new NIH format for biosketches:

NOT-OD-15-032: Update: New Biographical Sketch Format Required for NIH and AHRQ Grant Applications Submitted for Due Dates on or After May 25, 2015

Sunday, January 11th, 2015