Rare tRNAs driving protein folding paper

The gist is that it is important for protein folding to choose optimal and non-optimal synonymous codons, at different locations.
http://www.nature.com/nsmb/journal/v20/n2/full/nsmb.2466.html

An interesting paper! Nice to see codon usage revisited again. Another revisiting of codons (my own) is at
http://papers.gersteinlab.org/papers/revisit-cai

Evolutionary conservation of codon optimality reveals hidden signatures of cotranslational folding
Sebastian Pechmann & Judith Frydman
Nature Structural & Molecular Biology 20, 237–243 (2013) doi:10.1038/nsmb.2466

Tags: , ,

Leave a Reply